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EP6

编号: 25161
Cas号: 1353567-32-4
纯度: 98% Min.

EP6 is a 5-lipoxygenase (5-LO) inhibitor. 5-LO is a crucial enzyme of the arachidonic acid (AA) cascade and catalyzes the formation of bioactive leukotrienes (LTs) which are involved in inflammatory diseases and allergic reactions.

仅供研究使用。 我们不向患者出售。

化学信息

名称EP6
Iupac 化学名称N-Cyclohexyl-6-methyl-2-[4-(4-morpholinyl)phenyl]-imidazo[1,2-a]pyridin-3-amine
同义词EP6; EP-6; EP 6;
英文同义词EP6; EP-6; EP 6;
分子式C24H30N4O
分子量390.52
SmileCC1=CN2C(C=C1)=NC(C3=CC=C(N4CCOCC4)C=C3)=C2NC5CCCCC5
InChiKeyITCJJNJMYCQGTM-UHFFFAOYSA-N
InChiInChI=1S/C24H30N4O/c1-18-7-12-22-26-23(24(28(22)17-18)25-20-5-3-2-4-6-20)19-8-10-21(11-9-19)27-13-15-29-16-14-27/h7-12,17,20,25H,2-6,13-16H2,1H3
Cas号1353567-32-4
相关CAS号

订购信息

包装价格库存纯度备货期
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Request Bulk Quote Download MSDS 电话 : +86-177 0271 9238   Email : sales@sun-shinechem.com
外观性状类白色固体
纯度98% Min.
存储 0-4℃,可保存几天到几周;-20℃,可保存 几个月。
可溶性溶于DMSO等有机溶剂
处理方式
运输条件可以在室温下进行运输。
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

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Bisulfite Conversion of DNA: Performance Comparison of Different Kits and Methylation Quantitation of Epigenetic Biomarkers that Have the Potential to Be Used in Non-Invasive Prenatal Testing. PLoS One. 2015 Aug 6;10(8):e0135058. doi: 10.1371/journal.pone.0135058. eCollection 2015. PubMed PMID: 26247357; PubMed Central PMCID: PMC4527772. 5: Jeffery S, Morgan S. An unreported RFLP for probe 218 EP6 that is useful in linkage analysis of adult polycystic kidney disease. Hum Genet. 1993 Oct;92(4):428. PubMed PMID: 7901145. 6: Hajjaj F, Yoon ZS, Yoon MC, Park J, Satake A, Kim D, Kobuke Y. Assemblies of supramolecular porphyrin dimers in pentagonal and hexagonal arrays exhibiting light-harvesting antenna function. J Am Chem Soc. 2006 Apr 12;128(14):4612-23. PubMed PMID: 16594698. 7: Kumar V, Damodharan S, Pandaranayaka EP, Madathiparambil MG, Tennyson J. Molecular modeling and in-silico engineering of Cardamom mosaic virus coat protein for the presentation of immunogenic epitopes of Leptospira LipL32. J Biomol Struct Dyn. 2016;34(1):42-56. doi: 10.1080/07391102.2015.1009491. Epub 2015 Feb 18. PubMed PMID: 25692534. 8: Zhou Q, Xu J, Xie W, Li S, Li X. Linearity study of blood calcium test. Clin Lab. 2011;57(5-6):327-31. PubMed PMID: 21755822. 9: Ko DH, Jeong TD, Lee W, Chun S, Min WK. Performance Evaluation of a Restored Dimension TACR Assay: An Automated Platform for Measuring the Whole Blood Tacrolimus Concentration. Clin Lab. 2016;62(1-2):7-12. PubMed PMID: 27012028. 10: Günther V, Mueller D, von Eckardstein A, Saleh L. Head to head evaluation of the analytical performance of two commercial methotrexate immunoassays and comparison with liquid chromatography-mass spectrometry and the former fluorescence polarization immunoassay. Clin Chem Lab Med. 2016 May;54(5):823-31. doi: 10.1515/cclm-2015-0578. PubMed PMID: 26457783. 11: Maesa JM, Fernández-Riejos P, Mora CS, de Toro M, Valladares PM, González-Rodriguez C. Evaluation of Bio-Rad D-100 HbA1c analyzer against Tosoh G8 and Menarini HA-8180V. Pract Lab Med. 2016 May 14;5:57-64. doi: 10.1016/j.plabm.2016.05.002. eCollection 2016 Aug 1. PubMed PMID: 28856205; PubMed Central PMCID: PMC5574509. 12: Shipkova M, Vogeser M, Ramos PA, Verstraete AG, Orth M, Schneider C, Wallemacq P. Multi-center analytical evaluation of a novel automated tacrolimus immunoassay. Clin Biochem. 2014 Aug;47(12):1069-77. doi: 10.1016/j.clinbiochem.2014.03.023. Epub 2014 Apr 12. PubMed PMID: 24721684. 13: Li Y, Zhuang J, Huang X, Zhang Y, Lin D, Huang B, Qu P, Zeng J, Zhang X, Liu J, Xia F, Chen C. Performance evaluation of a new high throughput Mindray BS-2000M1 clinical chemistry system. Clin Biochem. 2014 Aug;47(12):1078-83. doi: 10.1016/j.clinbiochem.2014.03.020. Epub 2014 Apr 5. PubMed PMID: 24713398. 14: Greenwald I, Coulson A, Sulston J, Priess J. Correlation of the physical and genetic maps in the lin-12 region of Caenorhabditis elegans. Nucleic Acids Res. 1987 Mar 11;15(5):2295-307. PubMed PMID: 2882468; PubMed Central PMCID: PMC340635. 15: Schlacher A, Stanzer T, Osprian I, Mischitz M, Klingsbichel E, Faber K, Schwab H. Detection of a new enzyme for stereoselective hydrolysis of linalyl acetate using simple plate assays for the characterization of cloned esterases from Burkholderia gladioli. J Biotechnol. 1998 Jun 11;62(1):47-54. PubMed PMID: 9684341. 16: Vogeser M, Shipkova M, Rigo-Bonnin R, Wallemacq P, Orth M, Widmann M, Verstraete AG. Multicenter analytical evaluation of the automated electrochemiluminescence immunoassay for cyclosporine. Ther Drug Monit. 2014 Oct;36(5):640-50. doi: 10.1097/FTD.0000000000000068. PubMed PMID: 24646730; PubMed Central PMCID: PMC4218761. 17: Uhde K, Fischer R, Commandeur U. Expression of multiple foreign epitopes presented as synthetic antigens on the surface of Potato virus X particles. Arch Virol. 2005 Feb;150(2):327-40. Epub 2004 Oct 20. PubMed PMID: 15503224. 18: Paximadi E, Karakasiliotis I, Mamuris Z, Stathopoulos C, Krikelis V, Markoulatos P. Genomic analysis of recombinant sabin clinical isolates. Virus Genes. 2006 Apr;32(2):203-10. PubMed PMID: 16604453. 19: Distefano S, Palma JM, Gómez M, Río LA. Characterization of endoproteases from plant peroxisomes. Biochem J. 1997 Oct 15;327 ( Pt 2):399-405. PubMed PMID: 9359407; PubMed Central PMCID: PMC1218807. 20: Martinuzzo ME, Ujhelly C, Barrera LH, Adamo MA, Lopez MS, Otaso JC, Oyhamburu J. Validation of an Automated Immunoturbidimetric Assay for Fibrinogen/Fibrin Degradation Products Measurement and its Correlation to a Semi-Quantitative Latex Agglutination Test. Clin Lab. 2016 Nov 1;62(11):2085-2089. doi: 10.7754/Clin.Lab.2016.160223. PubMed PMID: 28164666.

化学结构

25161 - EP6 | CAS 1353567-32-4

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