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Dilmapimod

Catalog No.: 011312
Cas No.: 444606-18-2
Purity : 98% 
011312 - Dilmapimod | CAS 444606-18-2

Catalog number : 011312

CAS number : 444606-18-2

分子式 : C23H19F3N4O3 

分子量 : 456.417 

Iupac 化学名称 : 8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7-one 

Smile : CC1=C(C=CC(=C1)F)C2=C3C=CC(=O)N(C3=NC(=N2)NC(CO)CO)C4=C(C=CC=C4F)F

InChiKey : ORVNHOYNEHYKJG-UHFFFAOYSA-N

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同义词SB681323; SB 681323; SB-681323; GW 681323; GW-681323; GW681323 
英文同义词SB681323; SB 681323; SB-681323; GW 681323; GW-681323; GW681323 
分子式C23H19F3N4O3 
分子量456.417 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=C(C=CC(=C1)F)C2=C3C=CC(=O)N(C3=NC(=N2)NC(CO)CO)C4=C(C=CC=C4F)F
InChiKeyORVNHOYNEHYKJG-UHFFFAOYSA-N
InChiInChI=1S/C23H19F3N4O3/c1-12-9-13(24)5-6-15(12)20-16-7-8-19(33)30(21-17(25)3-2-4-18(21)26)22(16)29-23(28-20)27-14(10-31)11-32/h2-9,14,31-32H,10-11H2,1H3,(H,27,28,29)
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Dilmapimod is p38 MAPK inhibitor. SB-681323 inhibited the p38 MAPK pathway to a greater degree than prednisolone did. 

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