Difelikefalin
编号: 21257
Cas号: 1024828-77-0
纯度: ≧98.0%
Difelikefalin HCl is in stock.
Difelikefalin, also known CR-845; MR-13A-9; MR-13A9, is a novel and potent kappa opioid receptor agonist. CR845 exhibit low P450 CYP inhibition and low penetration into the brain. CR845 may be useful in the prophylaxis and treatment of pain and inflammation associated with a variety of diseases and conditions.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Difelikefalin |
|---|---|
| Iupac 化学名称 | 1-(D-phenylalanyl-D-phenylalanyl-D-leucyl-D-lysyl)-4-aminopiperidine-4-carboxylic acid |
| 同义词 | CR845 ; CR-845 ; CR 845 ; MR-13A-9 ; MR-13A9 ; Difelikefalin |
| 英文同义词 | CR845 ; CR-845 ; CR 845 ; MR-13A-9 ; MR-13A9 ; Difelikefalin |
| 分子式 | C36H53N7O6 |
| 分子量 | 679.86 |
| Smile | O=C(C1(N)CCN(C([C@@H](CCCCN)NC([C@@H](CC(C)C)NC([C@@H](CC2=CC=CC=C2)NC([C@@H](CC3=CC=CC=C3)N)=O)=O)=O)=O)CC1)O |
| InChiKey | FWMNVWWHGCHHJJ-SKKKGAJSSA-N |
| InChi | InChI=1S/C36H53N7O6/c1-24(2)21-29(32(45)40-28(15-9-10-18-37)34(47)43-19-16-36(39,17-20-43)35(48)49)42-33(46)30(23-26-13-7-4-8-14-26)41-31(44)27(38)22-25-11-5-3-6-12-25/h3-8,11-14,24,27-30H,9-10,15-23,37-39H2,1-2H3,(H,40,45)(H,41,44)(H,42,46)(H,48,49)/t27-,28-,29-,30-/m1/s1 |
| Cas号 | 1024828-77-0 |
| 相关CAS号 | 2413256-25-2(HCl); 1024829-44-4 (acetate) |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | 固体粉末 |
|---|---|
| 纯度 | ≧98.0% |
| 存储 | 短期（几天到几周）为0-4摄氏度，长期（几个月）为-20摄氏度 |
| 可溶性 | 可溶于DMSO |
| 处理方式 | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| 运输条件 | 作为非危险化学品在环境温度下装运。这种产品在正常运输和海关工作期间可以稳定几周 |
| 海关编码 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Cowan A, Kehner GB, Inan S. Targeting Itch with Ligands Selective for κ Opioid
Receptors. Handb Exp Pharmacol. 2015;226:291-314. doi:
10.1007/978-3-662-44605-8_16. Review. PubMed PMID: 25861786.
(Last update: 4/21/2016).
