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Defactinib

Catalog No.: 120111
Cas No.: 1073154-85-4
Purity : 98% 

Defactinib是一种有效的FAK磷酸化抑制剂;通过依赖AKT的途径克服抵抗YB - 1介导的紫杉醇。

For research use only. We do not sell to patients.

Chemical Information

名称Defactinib
Iupac 化学名称N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide 
同义词VS-6063; VS6063; VS 6063; PF04554878; PF-04554878; PF 04554878 
英文同义词VS-6063; VS6063; VS 6063; PF04554878; PF-04554878; PF 04554878 
分子式C20H21F3N8O3S 
分子量510.49 
SmileCNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F
InChiKeyFWLMVFUGMHIOAA-UHFFFAOYSA-N
InChiInChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)
Cas号1073154-85-4
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Ordering Information

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Formulation类白色至白色固体
纯度98% 
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO;不溶于水
Handling
运输条件可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

120111 - Defactinib | CAS 1073154-85-4

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