Cytosporone B
编号: 16122924
Cas号: 321661-62-5
纯度: 98%
Cytosporone B is the first naturally occurring agonist for nuclear orphan receptor Nur77. The molecule binds with high affinity (IC50=0.278 nM) to the ligand-binding domain of Nur77 and stimulates Nur77-dependent activities. Nur77 is also involved in glucose homeostasis, where it induces genes involved in gluconeogenesis. Csn-B physically binds to Nur77 and activates its transactivational activity and translocation to mitochondria to induce apoptosis. It inhibits cancer cell proliferation and tumor growth.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Cytosporone B |
|---|---|
| Iupac 化学名称 | Cytosporone B |
| 同义词 | N/A |
| 英文同义词 | N/A |
| 分子式 | C18H26O5 |
| 分子量 | 322.4 |
| Smile | CCCCCCCC(=O)c1c(cc(cc1O)O)CC(=O)OCC |
| InChiKey | UVVWQQKSNZLUQA-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H26O5/c1-3-5-6-7-8-9-15(20)18-13(11-17(22)23-4-2)10-14(19)12-16(18)21/h10,12,19,21H,3-9,11H2,1-2H3 |
| Cas号 | 321661-62-5 |
| MDL | MFCD12912406 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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