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Compound E

编号: 20575
Cas号: 209986-17-4
纯度: 98% Min.

Compound E is a cell-permeable, potent, selective inhibitor of ɣ-secretase and Notch processing.

仅供研究使用。 我们不向患者出售。

化学信息

名称Compound E
Iupac 化学名称(S,S)-2-[2-(3,5-Difluorophenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide
同义词Compound E; GSI-XXI; ɣ-secretase inhibitor XXI; GSI XXI; GSIXXI;
英文同义词Compound E; GSI-XXI; ɣ-secretase inhibitor XXI; GSI XXI; GSIXXI;
分子式C27H24F2N4O3
分子量490.50
SmileC[C@H](NC(CC1=CC(F)=CC(F)=C1)=O)C(N[C@H]2N=C(C3=CC=CC=C3)C4=CC=CC=C4N(C)C2=O)=O
InChiKeyJNGZXGGOCLZBFB-IVCQMTBJSA-N
InChiInChI=1S/C27H24F2N4O3/c1-16(30-23(34)14-17-12-19(28)15-20(29)13-17)26(35)32-25-27(36)33(2)22-11-7-6-10-21(22)24(31-25)18-8-4-3-5-9-18/h3-13,15-16,25H,14H2,1-2H3,(H,30,34)(H,32,35)/t16-,25+/m0/s1
Cas号209986-17-4
相关CAS号

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包装价格库存纯度备货期
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外观性状固体粉末
纯度98% Min.
存储短期(几天到几周)为0-4摄氏度,长期(几个月)为-20摄氏度
可溶性溶于DMSO
处理方式
运输条件作为非危险化学品在环境温度下装运。这种产品在正常运输和海关工作期间可以稳定几周.
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

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12: HENCH PS, SLOCUMB CH, et al. The effects of the adrenal cortical hormone 17-hydroxy-11-dehydrocorticosterone (Compound E) on the acute phase of rheumatic fever; preliminary report. Proc Staff Meet Mayo Clin. 1949 May 25;24(11):277-97. PubMed PMID: 18130001.

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化学结构

20575 - Compound E | CAS 209986-17-4

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