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Canertinib

编号: 16122909
Cas号: 289499-45-2
纯度: 98% 

Canertinib dihydrochloride is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. Canertinib binds to the intracellular domains of epidermal growth factor receptor tyrosine kinases (ErbB family), irreversibly inhibiting their signal transduction functions and resulting in tumor cell apoptosis and suppression of tumor cell proliferation. This agent also acts as a radiosensitizing agent and displays synergistic activity with other chemotherapeutic agents. 

仅供研究使用。 我们不向患者出售。

化学信息

名称Canertinib
Iupac 化学名称Canertinib 
同义词CI1033PD183805 
英文同义词CI1033PD183805 
分子式C24H27Cl3FN5O3 
分子量558.86 
SmileC=CC(=O)Nc1cc2c(cc1OCCCN3CCOCC3)ncnc2Nc4ccc(c(c4)Cl)F.Cl.Cl
InChiKeyJZZFDCXSFTVOJY-UHFFFAOYSA-N
InChiInChI=1S/C24H25ClFN5O3.2ClH/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16;;/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29);2*1H
Cas号289499-45-2
MDLMFCD09954112
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16122909 - Canertinib | CAS 289499-45-2

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