CPI-169 racemate is the racemate form of CPI-169, which is a novel and potent EZH2 inhibitor with IC50 <1 nM(inhibition of the catalytic activity of PRC2); decreases cellular levels of H3K27me3 with an EC50 of 70 nM, and triggers cell cycle arrest and apoptosis in a variety of cell lines.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | CPI-169(racemate) |
| 同义词 | 1-(1-(1-(Ethylsulfonyl)piperidin-4-yl)ethyl)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1H-indole-3-carboxamide |
| 英文同义词 | 1-(1-(1-(Ethylsulfonyl)piperidin-4-yl)ethyl)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1H-indole-3-carboxamide |
| 分子式 | C27H36N4O5S |
| 分子量 | 528.66 |
| InChiKey | |
| InChi | |
| Cas号 | 1450655-76-1 |
| 相关CAS号 | |
| 外观性状 | Solid powder |
| 纯度 | 97% |
| 存储 | -20 ºC for 3 years |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |