Zegocractin (CM-4620, Auxora(TM)) is a small-molecule inhibitor of the calcium release-activated calcium channel protein 1 (CRAC channel, ORAI1) .
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| 名称 | Zegocractin ( CM-4620 ) |
|---|---|
| Iupac 化学名称 | N-(5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide |
| 同义词 | CM-4620 ; CM 4620 ; CM4620 ; Zegocractin |
| 英文同义词 | CM-4620 ; CM 4620 ; CM4620 ; Zegocractin |
| 分子式 | C19H11ClF3N3O3 |
| 分子量 | 421.7602 |
| Smile | O=C(NC1=NC=C(C2=C(Cl)C=C(OC(F)(F)O3)C3=C2)N=C1)C4=C(C)C=CC=C4F |
| InChiKey | QQMKTHUGOQDEIL-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H11ClF3N3O3/c1-9-3-2-4-12(21)17(9)18(27)26-16-8-24-13(7-25-16)10-5-14-15(6-11(10)20)29-19(22,23)28-14/h2-8H,1H3,(H,25,26,27) |
| Cas号 | 1713240-67-5 |
| 相关CAS号 | 1713240-67-5 |
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Solid powder |
|---|---|
| 纯度 | ≧98.0% |
| 存储 | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Solubility:Soluble in DMSO |
| 可溶性 | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| 处理方式 | Refer to MSDS |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| 海关编码 | 2934200090 |
| Targets | Orai1 inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |