CHS-828
Catalog No: 100904
CAS Number: 200484-11-3
Purity: 98%
CHS-828, also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting the nuclear factor-kappaB translocation but unlikely through down-regulation of proteasome. CHS 828 has shown promising anticancer activity in experimental tumor models and primary cultures of cancer cells from patients.
仅供研究使用。 我们不向患者出售。
Chemical Information
| Name | CHS-828 |
|---|---|
| Iupac Chemical Name | (E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine |
| Synonyms | CHS 828; CHS828; GMX-1778; GMX1778; GMX 1778 |
| 英文同义词 | CHS 828; CHS828; GMX-1778; GMX1778; GMX 1778 |
| Molecular Formula | C19H22ClN5O |
| Molecular Weight | 371.86 |
| Smile | ClC1=CC=C(OCCCCCCN/C(=N\C#N)/NC2=CC=NC=C2)C=C1 |
| InChiKey | BOIPLTNGIAPDBY-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25) |
| CAS Number | 200484-11-3 |
| 相关CAS号 |
Ordering Information
| 包装 | Price | 库存 | Purity | 备货期 |
|---|---|---|---|---|
| 大货 | Enquiry | Enquiry | Enquiry |
| 外观性状 | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| 处理方式 | |
| Shipping Condition | Shipped under ambient temperature |
| 海关编码 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
