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CB-839

编号: 16122913
Cas号: 1439399-58-2
纯度: 98% 

CB-839 an is orally bioavailable inhibitor of glutaminase, with potential antineoplastic activity. Upon oral administration, CB-839 selectively and irreversibly inhibits glutaminase, a mitochondrial enzyme that is essential for the conversion of the amino acid glutamine into glutamate. By blocking glutamine utilization, proliferation in rapidly growing cells is impaired. Glutamine-dependent tumors rely on the conversion of exogenous glutamine into glutamate and glutamate metabolites to both provide energy and generate building blocks for the production of macromolecules, which are needed for cellular growth and survival. 

仅供研究使用。 我们不向患者出售。

化学信息

名称CB-839
Iupac 化学名称CB-839 
同义词CB839; CB-839; CB 839 
英文同义词CB839; CB-839; CB 839 
分子式C26H24F3N7O3S 
分子量571.57 
InChiKey
InChi
Cas号1439399-58-2
相关CAS号

订购信息

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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16122913 - CB-839 | CAS 1439399-58-2

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