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Bromosporine

Catalog No.: 16070108
Cas No.: 1619994-69-2
Purity : 98% by HPLC 
16070108 - Bromosporine | CAS 1619994-69-2

Catalog number : 16070108

CAS number : 1619994-69-2

分子式 : C17H20N6O4S 

分子量 : 404.4435 

Iupac 化学名称 : ethyl (3-methyl-6-(4-methyl-3-(methylsulfonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate 

Smile : CC1=NN=C2N1N=C(C=C2NC(OCC)=O)C2=CC(=C(C=C2)C)NS(=O)(=O)C

InChiKey : UYBRROMMFMPJAN-UHFFFAOYSA-N

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同义词Bromosporine 
英文同义词Bromosporine 
分子式C17H20N6O4S 
分子量404.4435 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=NN=C2N1N=C(C=C2NC(OCC)=O)C2=CC(=C(C=C2)C)NS(=O)(=O)C
InChiKeyUYBRROMMFMPJAN-UHFFFAOYSA-N
InChiInChI=1S/C17H20N6O4S/c1-5-27-17(24)18-15-9-14(21-23-11(3)19-20-16(15)23)12-7-6-10(2)13(8-12)22-28(4,25)26/h6-9,22H,5H2,1-4H3,(H,18,24)
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Bromosporine is a broad spectrum inhibitor for bromodomains and as such will be very useful in elucidating further biological roles of reader domains as well as a tool for the validation of functional assays. Proteins that contain BRDs have been implicated in the development of a large variety of diseases, including various cancers, inflammatory diseases and neurological diseases and the therapeutic potential of bromodomain inhibition has been shown in several of these diseases, such as HIV, cancer and inflammation. 

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