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Blu667

Catalog No.: 191282
Cas No.: 2097132-94-8
Purity : >98%

BLU-667是一种有效的选择性 RET 抑制剂, IC50 为0.4 nM,对突变体 RET V804L / RET V804M / RET M918T也有效, IC50 为0.3 nM/0.4 nM/0.4 nM。

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Chemical Information

名称Blu667
同义词BLU-667;BLU667.
英文同义词BLU-667;BLU667.
分子式C27H32FN9O2
分子量533.61
SmileO=C([C@@]1(OC)CC[C@@H](C2=NC(NC3=NNC(C)=C3)=CC(C)=N2)CC1)N[C@H](C4=CC=C(N5N=CC(F)=C5)N=C4)C
InChiKey
InChiInChI=1S/C27H32FN9O2/c1-16-11-22(33-23-12-17(2)35-36-23)34-25(31-16)19-7-9-27(39-4,10-8-19)26(38)32-18(3)20-5-6-24(29-13-20)37-15-21(28)14-30-37/h5-6,11-15,18-19H,7-10H2,1-4H3,(H,32,38)(H2,31,33,34,35,36)/t18-,19-,27-/m0/s1
Cas号2097132-94-8
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Ordering Information

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Formulation类白色至白色固体
纯度>98%
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO
Handling
运输条件可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

191282 - Blu667  | CAS 2097132-94-8

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