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BYK204165

Catalog No.: 16071031
Cas No.: 1104546-89-5
Purity : 98% by HPLC 
16071031 - BYK204165 | CAS 1104546-89-5

Catalog number : 16071031

CAS number : 1104546-89-5

分子式 : C15H12N2O2 

分子量 : 252.27 

Iupac 化学名称 : (4Z)-4-[(1-methylpyrrol-2-yl)methylidene]isoquinoline-1,3-dione 

Smile : CN1C(=CC=C1)\C=C\1/C(NC(C2=CC=CC=C12)=O)=O

InChiKey : BTYSIDSTHDDAJW-LCYFTJDESA-N

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同义词BYK204165; BYK-204165 
英文同义词BYK204165; BYK-204165 
分子式C15H12N2O2 
分子量252.27 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCN1C(=CC=C1)\C=C\1/C(NC(C2=CC=CC=C12)=O)=O
InChiKeyBTYSIDSTHDDAJW-LCYFTJDESA-N
InChiInChI=1S/C15H12N2O2/c1-17-8-4-5-10(17)9-13-11-6-2-3-7-12(11)14(18)16-15(13)19/h2-9H,1H3,(H,16,18,19)/b13-9-
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 BYK204165 is a potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively). BYK204165 was found to be 100-fold more selective for PARP-1. BYK204165 might be novel and valuable tool for investigating PARP-1-mediated effects. 

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