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BMS-794833

Catalog No.: 52205
Cas No.: 1174046-72-0
Purity : 98% 
52205 - BMS-794833 | CAS 1174046-72-0

Catalog number : 52205

CAS number : 1174046-72-0

分子式 : C23H15ClF2N4O3 

分子量 : 468.84 

Iupac 化学名称 : N-(4-((2-amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)-5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxamide 

Smile : NC1=NC=CC(=C1Cl)OC1=C(C=C(C=C1)NC(=O)C1=CNC=C(C1=O)C1=CC=C(C=C1)F)F

InChiKey : PDYXPCKITKHFOZ-UHFFFAOYSA-N

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同义词N/A 
英文同义词N/A 
分子式C23H15ClF2N4O3 
分子量468.84 
外观solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 
SmileNC1=NC=CC(=C1Cl)OC1=C(C=C(C=C1)NC(=O)C1=CNC=C(C1=O)C1=CC=C(C=C1)F)F
InChiKeyPDYXPCKITKHFOZ-UHFFFAOYSA-N
InChiInChI=1S/C23H15ClF2N4O3/c24-20-19(7-8-29-22(20)27)33-18-6-5-14(9-17(18)26)30-23(32)16-11-28-10-15(21(16)31)12-1-3-13(25)4-2-12/h1-11H,(H2,27,29)(H,28,31)(H,30,32)
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BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7/15 nM; also inhibits Ron, Axl and Flt3 with IC50 of<3 nM; a prodrug of BMS-817378. 

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