BMS-3
编号: 16071026
Cas号: 1338247-30-5
纯度: 98% by HPLC
BMS-3 is a LIM kinase 1 (LIMK1) inhibitor. LIMK inhibition with 1 M BMS-3 damaged MTOC protein localisation to spindle poles, undermined the formation and positioning of functional MTOC and thus disrupted spindle formation and chromosome alignment. These effects were phenocopied by microinjection of LIMK1 antibody into mouse oocytes. LIM kinase 1 (LIMK1) activity is essential for cell migration and cell cycle progression.
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化学信息
| 名称 | BMS-3 |
|---|---|
| Iupac 化学名称 | N-[5-[2-(2,6-Dichlorophenyl)-5-(difluoromethyl)pyrazol-3-yl]-1,3-thiazol-2-yl]cyclopropanecarboxamide |
| 同义词 | BMS-3; BMS 3 |
| 英文同义词 | BMS-3; BMS 3 |
| 分子式 | C17H12Cl2F2N4OS |
| 分子量 | 429.2668 |
| Smile | ClC1=C(C(=CC=C1)Cl)N1N=C(C=C1C1=CN=C(S1)NC(=O)C1CC1)C(F)F |
| InChiKey | YBGGBHCJSAEIAS-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H12Cl2F2N4OS/c18-9-2-1-3-10(19)14(9)25-12(6-11(24-25)15(20)21)13-7-22-17(27-13)23-16(26)8-4-5-8/h1-3,6-8,15H,4-5H2,(H,22,23,26) |
| Cas号 | 1338247-30-5 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
