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BMN 673

Catalog No.: 122946
Cas No.: 1207456-01-6
Purity : 98% 
122946 - BMN 673 | CAS 1207456-01-6

Catalog number : 122946

CAS number : 1207456-01-6

分子式 : C19H14F2N6O 

分子量 : 380.351 

Iupac 化学名称 : (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one 

Smile : CN1C(=NC=N1)C2C(N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F

InChiKey : IUEWAGVJRJORLA-UHFFFAOYSA-N

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同义词Talazoparib; BMN673; BMN 673 
英文同义词Talazoparib; BMN673; BMN 673 
分子式C19H14F2N6O 
分子量380.351 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCN1C(=NC=N1)C2C(N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F
InChiKeyIUEWAGVJRJORLA-UHFFFAOYSA-N
InChiInChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,25H,1H3,(H,26,28)
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BMN 673 is a novel PARP1/2 inhibitor with IC50 of 0.58 nM(PARP1); does not inhibit PARG and is highly sensitive to PTEN mutation. 

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