BAZ2-ICR
Catalog No.: 111907
Cas No.: 1665195-94-7
Purity : 98%
Catalog number : 111907
CAS number : 1665195-94-7
分子式 : C20H19N7
分子量 : 357.4
化学名称 : BAZ2-ICR
Smile : CN1C=C(CCN2C=NC(C3=CN(C)N=C3)=C2C4=CC=C(C#N)C=C4)C=N1
InChiKey : RRZVGDGTWNQAPW-UHFFFAOYSA-N
| Packaging | Price | Availability | Purity | Estimated Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry |
| 同义词 | 4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile |
|---|---|
| 英文同义词 | 4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile |
| 分子式 | C20H19N7 |
| 分子量 | 357.4 |
| 外观 | Solid powder |
| 纯度 | 98% |
| 可溶性 | Soluble in DMSO |
| 存储 | -20 ºC for 3 years |
| 运输条件 | Shipped under ambient temperature |
| Smile | CN1C=C(CCN2C=NC(C3=CN(C)N=C3)=C2C4=CC=C(C#N)C=C4)C=N1 |
| InChiKey | RRZVGDGTWNQAPW-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3 |
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BAZ2-ICR is a small molecule inhibitor of BAZ2A (Kd = 109 nM; IC50 = 130 nM) and BAZ2B (Kd = 170 nM; IC50 = 180 nM) bromodomains. It demonstrates 15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains.
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