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BAZ2-ICR

Catalog No.: 111907
Cas No.: 1665195-94-7
Purity : 98% 
111907 - BAZ2-ICR | CAS 1665195-94-7

Catalog number : 111907

CAS number : 1665195-94-7

分子式 : C20H19N7 

分子量 : 357.4 

化学名称 : BAZ2-ICR

Smile : CN1C=C(CCN2C=NC(C3=CN(C)N=C3)=C2C4=CC=C(C#N)C=C4)C=N1

InChiKey : RRZVGDGTWNQAPW-UHFFFAOYSA-N

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同义词4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile 
英文同义词4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile 
分子式C20H19N7 
分子量357.4 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCN1C=C(CCN2C=NC(C3=CN(C)N=C3)=C2C4=CC=C(C#N)C=C4)C=N1
InChiKeyRRZVGDGTWNQAPW-UHFFFAOYSA-N
InChiInChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
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BAZ2-ICR is a small molecule inhibitor of BAZ2A (Kd = 109 nM; IC50 = 130 nM) and BAZ2B (Kd = 170 nM; IC50 = 180 nM) bromodomains. It demonstrates 15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains. 

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