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Avatrombopag

Catalog No.: 16122860
Cas No.: 570406-98-3
Purity : 98% 
16122860 - Avatrombopag | CAS 570406-98-3

Catalog number : 16122860

CAS number : 570406-98-3

分子式 : C29H34Cl2N6O3S2 

分子量 : 649.65 

Iupac 化学名称 : Avatrombopag 

Smile : c1c(cnc(c1Cl)N2CCC(CC2)C(=O)O)C(=O)Nc3nc(c(s3)N4CCN(CC4)C5CCCCC5)c6cc(cs6)Cl

InChiKey : OFZJKCQENFPZBH-UHFFFAOYSA-N

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同义词AKR501; AKR 501; AKR-501; YM477; YM-477; YM 477; E5501; AS 1670542; AS1670542; AS-1670542; Avatrombopag 
英文同义词AKR501; AKR 501; AKR-501; YM477; YM-477; YM 477; E5501; AS 1670542; AS1670542; AS-1670542; Avatrombopag 
分子式C29H34Cl2N6O3S2 
分子量649.65 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
Smilec1c(cnc(c1Cl)N2CCC(CC2)C(=O)O)C(=O)Nc3nc(c(s3)N4CCN(CC4)C5CCCCC5)c6cc(cs6)Cl
InChiKeyOFZJKCQENFPZBH-UHFFFAOYSA-N
InChiInChI=1S/C29H34Cl2N6O3S2/c30-20-15-23(41-17-20)24-27(37-12-10-35(11-13-37)21-4-2-1-3-5-21)42-29(33-24)34-26(38)19-14-22(31)25(32-16-19)36-8-6-18(7-9-36)28(39)40/h14-18,21H,1-13H2,(H,39,40)(H,33,34,38)
MDLMFCD18633249
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Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 may be useful in the treatment of patients with thrombocytopenia. 

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