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Asciminib

Catalog No.: 1711222
Cas No.: 1492952-76-7
Purity : >98%

Asciminib, 也叫ABL001,是一种有效的BCR-ABL的变构抑制剂。ABL001在与尼罗替尼联合在体内的慢性骨髓性白血病模型中,防止出现耐药性疾病。

For research use only. We do not sell to patients.

Chemical Information

名称Asciminib
Iupac 化学名称(R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide
同义词ABL-001; AB -001; ABL001; asciminib
英文同义词ABL-001; AB -001; ABL001; asciminib
分子式C20H18ClF2N5O3
分子量449.8428
SmileO=C(NC1=CC=C(OC(F)(Cl)F)C=C1)C2=CN=C(N3C[C@H](O)CC3)C(C4=CC=NN4)=C2
InChiKeyVOVZXURTCKPRDQ-CQSZACIVSA-N
InChiInChI=1S/C20H18ClF2N5O3/c21-20(22,23)31-15-3-1-13(2-4-15)26-19(30)12-9-16(17-5-7-25-27-17)18(24-10-12)28-8-6-14(29)11-28/h1-5,7,9-10,14,29H,6,8,11H2,(H,25,27)(H,26,30)/t14-/m1/s1
Cas号1492952-76-7
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Ordering Information

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Formulation 类白色至白色固体
纯度>98%
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO;不溶于水
Handling
运输条件可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

1711222 - Asciminib | CAS 1492952-76-7

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