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Asapiprant

Catalog No.: 2051515
Cas No.: 932372-01-5
Purity : 98% Min.
2051515 - Asapiprant | CAS 932372-01-5

Catalog number : 2051515

CAS number : 932372-01-5

分子式 : C24H27N3O7S

分子量 : 501.55

Iupac 化学名称 : 2-(5-(4-((4-Isopropoxyphenyl)sulfonyl)piperazin-1-yl)-2-(oxazol-2-yl)phenoxy)acetic acid

Smile : C(C)(C)OC1=CC=C(C=C1)S(=O)(=O)N1CCN(CC1)C=1C=CC(=C(OCC(=O)O)C1)C=1OC=CN1

InChiKey : ZMZNWNTZRWXTJU-UHFFFAOYSA-N

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同义词Asapiprant,S-555739; S 555739; S555739
英文同义词Asapiprant,S-555739; S 555739; S555739
分子式C24H27N3O7S
分子量501.55
外观 类白色至白色固体
纯度98% Min.
可溶性可溶于DMSO;不溶于水
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
SmileC(C)(C)OC1=CC=C(C=C1)S(=O)(=O)N1CCN(CC1)C=1C=CC(=C(OCC(=O)O)C1)C=1OC=CN1
InChiKeyZMZNWNTZRWXTJU-UHFFFAOYSA-N
InChiInChI=1S/C24H27N3O7S/c1-17(2)34-19-4-6-20(7-5-19)35(30,31)27-12-10-26(11-13-27)18-3-8-21(24-25-9-14-32-24)22(15-18)33-16-23(28)29/h3-9,14-15,17H,10-13,16H2,1-2H3,(H,28,29)
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Asapiprant 是一个强效且有选择性的 DP1 受体拮抗剂,其 Ki 值为 0.44 nM。

Effect of the potent and selective DP1 receptor antagonist, asapiprant (S-555739), in animal models of allergic rhinitis and allergic asthma.
Takahashi G, et al. Eur J Pharmacol. 2015 Oct 15;765:15-23. PMID: 26277322.

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