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Arry-380

Catalog No.: 021801
Cas No.: 937265-83-3
Purity : 98% 
021801 - Arry-380 | CAS 937265-83-3

Catalog number : 021801

CAS number : 937265-83-3

分子式 : C29H27N7O4S 

分子量 : 569.634 

Iupac 化学名称 : 6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine 

Smile : CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5

InChiKey : QVMNYGOVNWWFKF-UHFFFAOYSA-N

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同义词ARRY380; ARRY 380 
英文同义词ARRY380; ARRY 380 
分子式C29H27N7O4S 
分子量569.634 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5
InChiKeyQVMNYGOVNWWFKF-UHFFFAOYSA-N
InChiInChI=1S/C29H27N7O4S/c1-19-13-21(4-7-26(19)39-22-9-11-36-28(15-22)32-18-34-36)35-29-24-14-20(3-6-25(24)31-17-33-29)27-8-5-23(40-27)16-30-10-12-41(2,37)38/h3-9,11,13-15,17-18,30H,10,12,16H2,1-2H3,(H,31,33,35)
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ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR. 

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