Argatroban
编号: 16122858
Cas号: 141396-28-3
纯度: 98%
Argatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). Argatroban is a direct thrombin inhibitor that reversibly binds to the thrombin active site. Argatroban exerts its anticoagulant effects by inhibiting thrombin-catalyzed or -induced reactions, including fibrin formation; activation of coagulation factors V, VIII, and XIII; activation of protein C; and platelet aggregation. Argatroban inhibits thrombin with an inhibition constant (Ki) of 0.04 M.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Argatroban |
|---|---|
| Iupac 化学名称 | Argatroban |
| 同义词 | MCI-9038; MCI9038; MCI9038; MD805; MD-805; MD 805; MMTQAP; MPQA |
| 英文同义词 | MCI-9038; MCI9038; MCI9038; MD805; MD-805; MD 805; MMTQAP; MPQA |
| 分子式 | C23H36N6O5S |
| 分子量 | 508.64 |
| Smile | C[C@@H]1CCN([C@H](C1)C(=O)O)C(=O)[C@H](CCCNC(=N)N)NS(=O)(=O)c2cccc3c2NCC(C3)C.O |
| InChiKey | AIEZTKLTLCMZIA-CZSXTPSTSA-N |
| InChi | InChI=1S/C23H36N6O5S.H2O/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19;/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26);1H2/t14-,15?,17+,18-;/m1./s1 |
| Cas号 | 141396-28-3 |
| MDL | MFCD00895735 |
| 相关CAS号 |
订购信息
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| 大货 | 询价 | 询价 | 询价 |
