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Altiratinib

Catalog No.: 120104
Cas No.: 1345847-93-9
Purity : 98% 
120104 - Altiratinib | CAS 1345847-93-9

Catalog number : 120104

CAS number : 1345847-93-9

分子式 : C26H21F3N4O4 

分子量 : 510.46 

Iupac 化学名称 : 1-N'-[4-[2-(cyclopropanecarbonylamino)pyridin-4-yl]oxy-2,5-difluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 

Smile : C1CC1C(=O)NC2=NC=CC(=C2)OC3=C(C=C(C(=C3)F)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F)F

InChiKey : GNNDEPIMDAZHRQ-UHFFFAOYSA-N

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同义词DCC2701; DCC 2701; DCC-2701; DP 5164; DP5164; DP-5164 
英文同义词DCC2701; DCC 2701; DCC-2701; DP 5164; DP5164; DP-5164 
分子式C26H21F3N4O4 
分子量510.46 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileC1CC1C(=O)NC2=NC=CC(=C2)OC3=C(C=C(C(=C3)F)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F)F
InChiKeyGNNDEPIMDAZHRQ-UHFFFAOYSA-N
InChiInChI=1S/C26H21F3N4O4/c27-15-3-5-16(6-4-15)31-24(35)26(8-9-26)25(36)32-20-12-19(29)21(13-18(20)28)37-17-7-10-30-22(11-17)33-23(34)14-1-2-14/h3-7,10-14H,1-2,8-9H2,(H,31,35)(H,32,36)(H,30,33,34)
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Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. 

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