Alixorexton
编号: 25120
Cas号: 2648347-56-0
纯度: 98% Min.
Alixorexton, also known as TAK-994 or firazorexton, is a potent, orally bioavailable, brain-penetrant agonist that selectively targets the orexin 2 receptor (OX2R), with additional activity at the orexin 1 receptor (OX1R). Its mechanism of action involves mimicking the endogenous orexin neuropeptides, thereby promoting wakefulness. Preclinical studies have demonstrated that Alixorexton effectively suppresses fragmentation of wakefulness and reduces cataplexy-like episodes in mouse models of narcolepsy, indicating its potential as a therapeutic agent for sleep disorders.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Alixorexton |
|---|---|
| Iupac 化学名称 | N-((21S,24S,52R,53S)-6-oxo-3,8-dioxa-5(2,1)-piperidina-1(1,2)-benzena-2(1,4)-cyclohexanacyclooctaphane-53-yl)methanesulfonamide |
| 同义词 | Alixorexton; firazorexton; TAK-994; TAK 994; TAK994; |
| 英文同义词 | Alixorexton; firazorexton; TAK-994; TAK 994; TAK994; |
| 分子式 | C21H30N2O5S |
| 分子量 | 422.54 |
| Smile | O=C(N1[C@@]([H])(CO2)[C@](NS(=O)(C)=O)([H])CCC1)COC3=CC=CC=C3[C@]4([H])CC[C@@]2([H])CC4 |
| InChiKey | IHNJMACFBQEKRJ-NBMJBFSESA-N |
| InChi | InChI=1S/C21H30N2O5S/c1-29(25,26)22-18-6-4-12-23-19(18)13-27-16-10-8-15(9-11-16)17-5-2-3-7-20(17)28-14-21(23)24/h2-3,5,7,15-16,18-19,22H,4,6,8-14H2,1H3/t15-,16+,18-,19-/m0/s1 |
| Cas号 | 2648347-56-0 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Off-white solid |
|---|---|
| 纯度 | 98% Min. |
| 存储 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| 海关编码 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
