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Alda 1

Catalog No.: 102702
Cas No.: 349438-38-6
Purity : 98% 
102702 - Alda 1 | CAS 349438-38-6

Catalog number : 102702

CAS number : 349438-38-6

分子式 : C15H11Cl2NO3 

分子量 : 324.159 

Iupac 化学名称 : N-(1,3-Benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide 

Smile : O1COC2=C1C=CC(=C2)CNC(C2=C(C=CC=C2Cl)Cl)=O

InChiKey : NMKJFZCBCIUYHI-UHFFFAOYSA-N

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同义词ALDH2 Agonist 
英文同义词ALDH2 Agonist 
分子式C15H11Cl2NO3 
分子量324.159 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileO1COC2=C1C=CC(=C2)CNC(C2=C(C=CC=C2Cl)Cl)=O
InChiKeyNMKJFZCBCIUYHI-UHFFFAOYSA-N
InChiInChI=1S/C15H11Cl2NO3/c16-10-2-1-3-11(17)14(10)15(19)18-7-9-4-5-12-13(6-9)21-8-20-12/h1-6H,7-8H2,(H,18,19)
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Alda 1 is a cell-permeable benzamide compound that selectively enhances the activity of both the wild-type ALDH2*1 and the east asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (2.1-, 2.2, and 11-fold activation of 20 g wt homo, wt/mut hetero, and mut homo tetramer, respectively, at 100 M), while exhibiting no effect toward alcohol dehydrogenase 1, cytosolic ALDH1, or mitochondrial ALDH5. 

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