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AZD8186

Catalog No.: 122925
Cas No.: 1627494-13-6
Purity : 98% 
122925 - AZD8186 | CAS 1627494-13-6

Catalog number : 122925

CAS number : 1627494-13-6

分子式 : C24H25F2N3O4 

分子量 : 457.470 

Iupac 化学名称 : 8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide 

Smile : CC(C1=C2C(=CC(=C1)C(=O)N(C)C)C(=O)C=C(O2)N3CCOCC3)NC4=CC(=CC(=C4)F)F

InChiKey : LMJFJIDLEAWOQJ-UHFFFAOYSA-N

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同义词AZD-8186 
英文同义词AZD-8186 
分子式C24H25F2N3O4 
分子量457.470 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC(C1=C2C(=CC(=C1)C(=O)N(C)C)C(=O)C=C(O2)N3CCOCC3)NC4=CC(=CC(=C4)F)F
InChiKeyLMJFJIDLEAWOQJ-UHFFFAOYSA-N
InChiInChI=1S/C24H25F2N3O4/c1-14(27-18-11-16(25)10-17(26)12-18)19-8-15(24(31)28(2)3)9-20-21(30)13-22(33-23(19)20)29-4-6-32-7-5-29/h8-14,27H,4-7H2,1-3H3
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AZD8186 is an isoform-specific small-molecule PI3K inhibitor, potently inhibits PI3K (IC50=4 nM) and PI3K (IC50=12 nM) with selectivity over PI3K (IC50=35 nM) and PI3K (IC50=675 nM). 

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