AZD3759
编号: 901301
Cas号: 1626387-80-1
纯度: ≧99.0%
AZD3759 is an orally available inhibitor of the epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Upon oral administration, AZD3759 binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR. This prevents EGFR-mediated signaling, and may lead to both induction of cell death and inhibition of tumor growth in EGFR-overexpressing cells. EGFR, a receptor tyrosine kinase mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization. Check for active clinical trials using this agent. (NCI Thesaurus)
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | AZD3759 |
|---|---|
| Iupac 化学名称 | (R)-4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate |
| 同义词 | AZD-3759;AZD3759;AZD 3759 |
| 英文同义词 | AZD-3759;AZD3759;AZD 3759 |
| 分子式 | C22H23ClFN5O3 |
| 分子量 | 459.90 |
| Smile | COC1=C(OC(N2[C@H](C)CN(C)CC2)=O)C=C3C(N=CN=C3NC4=CC=CC(Cl)=C4F)=C1 |
| InChiKey | MXDSJQHFFDGFDK-CYBMUJFWSA-N |
| InChi | InChI=1S/C22H23ClFN5O3/c1-13-11-28(2)7-8-29(13)22(30)32-19-9-14-17(10-18(19)31-3)25-12-26-21(14)27-16-6-4-5-15(23)20(16)24/h4-6,9-10,12-13H,7-8,11H2,1-3H3,(H,25,26,27)/t13-/m1/s1 |
| Cas号 | 1626387-80-1 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
