+86-27-65522453 sales@sun-shinechem.com

AS101

Catalog No.: 161227106
Cas No.: 106566-58-9
Purity : 98% 
161227106 - AS101 | CAS 106566-58-9

Catalog number : 161227106

CAS number : 106566-58-9

分子式 : C2H4Cl3O2Te.H4N 

分子量 : 312.05 

Iupac 化学名称 : AS101 

Smile : C1CO[Te-](O1)(Cl)(Cl)Cl.[NH4+]

InChiKey : AXWLPMGUUAIGJK-UHFFFAOYSA-O

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDS电话:+86-27-65522453 | Email:sales@sun-shinechem.com
同义词N/A 
英文同义词N/A 
分子式C2H4Cl3O2Te.H4N 
分子量312.05 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
SmileC1CO[Te-](O1)(Cl)(Cl)Cl.[NH4+]
InChiKeyAXWLPMGUUAIGJK-UHFFFAOYSA-O
InChiInChI=1S/C2H4Cl3O2Te.H3N/c3-8(4,5)6-1-2-7-8;/h1-2H2;1H3/q-1;/p+1
MDLMFCD01682758
Coming soon.
AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.AS101 downregulates IL-18 and IL-1 serum levels in a mouse model of lipopolysaccharide (LPS)-induced sepsis, resulting in increased survival. It has also been shown to be protective against lethal and sublethal effects of irradiation and chemotherapy. In a model of cecal ligation and puncture (CLP)-induced sepsis in mice, AS101 also exerted beneficial effects[1]. AS101 treated rats showed a large increase in SIRT1 protein levels in the liver and kidney extracts of rats treated with AS101. AS101 prevents development of insulin resistance in vivo. AS101 affects SIRT1 related metabolic pathways by changing the insulin levels. AS101 treatment prevents hyperglycemia associated with T2D(type 2 diabetes) and some of the symptoms of the disease in the HFD(high fat diet)+STZ(Streptozotocin) rat model 

106566-58-9 - Request Bulk Quote

×
106566-58-9 - Request Bulk Quote
Change