AMXT-1501 ( AMX-513 ) is a novel inhibitor of the polyamine transport system. AMXT1501 blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells.
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Name | AMXT-1501 ( AMX-513 ) |
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Iupac Chemical Name | N1-[3-[4-(3-Aminopropylamino)butylamino]propyl]-N6-(hexadecanoyl)l-D-lysinamide |
Synonyms | AMX-513 ; AMXT-1501 ; AMX513 ; AMXT1501 ; AMX 513 ; AMXT 1501 ; |
英文同义词 | AMX-513 ; AMXT-1501 ; AMX513 ; AMXT1501 ; AMX 513 ; AMXT 1501 ; |
Molecular Formula | C32H68N6O2 |
Molecular Weight | 568.92 |
Smile | CCCCCCCCCCCCCCCC(NCCCC[C@@H](N)C(NCCCNCCCCNCCCN)=O)=O |
InChiKey | USNCWPSRPOWEBG-SSEXGKCCSA-N |
InChi | InChI=1S/C32H68N6O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-22-31(39)37-28-16-15-21-30(34)32(40)38-29-20-27-36-25-18-17-24-35-26-19-23-33/h30,35-36H,2-29,33-34H2,1H3,(H,37,39)(H,38,40)/t30-/m1/s1 |
CAS Number | 441022-64-6 |
相关CAS号 | 441022-64-6 |
包装 | Price | 库存 | Purity | 备货期 |
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大货 | Enquiry | Enquiry | Enquiry |
外观性状 | Off-white to light-yellow solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
处理方式 | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
海关编码 | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study | Phase 1 Clinical Trial |