AM-2394
编号: 16122855
Cas号: 1442684-77-6
纯度: 98%
AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394 activates GK with an EC50 of 60 nM, increases the affinity of GK for glucose by approximately 10-fold, exhibits moderate clearance and good oral bioavailability in multiple animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | AM-2394 |
|---|---|
| Iupac 化学名称 | AM-2394 |
| 同义词 | AM 2394; AM2394 |
| 英文同义词 | AM 2394; AM2394 |
| 分子式 | C22H25N5O4 |
| 分子量 | 423.473 |
| InChiKey | |
| InChi | |
| Cas号 | 1442684-77-6 |
| 相关CAS号 |
订购信息
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