AM-2394
Catalog No.: 16122855
Cas No.: 1442684-77-6
Purity : 98%
Catalog number : 16122855
CAS number : 1442684-77-6
分子式 : C22H25N5O4
分子量 : 423.473
Iupac 化学名称 : AM-2394
InChiKey :
| Packaging | Price | Availability | Purity | Estimated Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry |
| 同义词 | AM 2394; AM2394 |
|---|---|
| 英文同义词 | AM 2394; AM2394 |
| 分子式 | C22H25N5O4 |
| 分子量 | 423.473 |
| 外观 | crystalline solid |
| 纯度 | 98% |
| 可溶性 | Soluble in DMSO |
| 存储 | 3 years -20ºCpowder |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
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AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394 activates GK with an EC50 of 60 nM, increases the affinity of GK for glucose by approximately 10-fold, exhibits moderate clearance and good oral bioavailability in multiple animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes.
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