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AG 490

Catalog No.: 122210
Cas No.: 134036-52-5
Purity : 98% 
122210 - AG 490 | CAS 134036-52-5

Catalog number : 122210

CAS number : 134036-52-5

分子式 : C17H14N2O3 

分子量 : 294.305 

Iupac 化学名称 : N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide 

Smile : C1=CC=C(C=C1)CNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N

InChiKey : TUCIOBMMDDOEMM-RIYZIHGNSA-N

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同义词Tyrphostin B42 
英文同义词Tyrphostin B42 
分子式C17H14N2O3 
分子量294.305 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileC1=CC=C(C=C1)CNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N
InChiKeyTUCIOBMMDDOEMM-RIYZIHGNSA-N
InChiInChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
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AG-490 is a tyrosine kinase inhibitor of JAK2, EGFR, and Neu that belongs to the family of tyrphostins. In acute lymphoblastic leukemia studies the compound has been reported to inhibit JAK2 from B cell precursors. 

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