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ACY-738

Catalog No.: 161227114
Cas No.: 1375465-91-0
Purity : 98% 
161227114 - ACY-738 | CAS 1375465-91-0

Catalog number : 161227114

CAS number : 1375465-91-0

分子式 : C14H14N4O2 

分子量 : 270.292 

Iupac 化学名称 : N-Hydroxy-2-[(1-phenylcyclopropyl)amino]-5-pyrimidinecarboxamide 

Smile : ONC(=O)C=1C=NC(=NC1)NC1(CC1)C1=CC=CC=C1

InChiKey : LIIWIMDSZVNYHY-UHFFFAOYSA-N

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同义词ACY-738; ACY 738; ACY738 
英文同义词ACY-738; ACY 738; ACY738 
分子式C14H14N4O2 
分子量270.292 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
SmileONC(=O)C=1C=NC(=NC1)NC1(CC1)C1=CC=CC=C1
InChiKeyLIIWIMDSZVNYHY-UHFFFAOYSA-N
InChiInChI=1S/C14H14N4O2/c19-12(18-20)10-8-15-13(16-9-10)17-14(6-7-14)11-4-2-1-3-5-11/h1-5,8-9,20H,6-7H2,(H,18,19)(H,15,16,17)
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ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.  

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