3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3K with IC50 of 25 M and 60 M; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation.
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Name | 3-Methyladenine (3-MA) |
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Molecular Formula | C6H7N5 |
Molecular Weight | 149.15 |
Smile | Cn1cnc(c-2ncnc12)N |
InChiKey | DLUQBLYJIRLSSC-UHFFFAOYSA-N |
InChi | InChI=1S/C6H15N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h4-6,8-10H,2-3,7H2,1H3 |
CAS Number | 5142-23-4 |
MDL | MFCD00010531 |
相关CAS号 |
包装 | Price | 库存 | Purity | 备货期 |
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大货 | Enquiry | Enquiry | Enquiry |
Purity | 98% |
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处理方式 | |
海关编码 |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |