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Semaxanib (SU5416)

Catalog No: 51803
CAS Number: 204005-46-9
Purity: 98% 

Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 M, 20-fold more selective for VEGFR than PDGFR, lack of activity against EGFR, InsR and FGFR. Phase 3. 

For research use only. We do not sell to patients.

Chemical Information

NameSemaxanib (SU5416)
Iupac Chemical Name2H-Indol-2-one,3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)- 
SynonymsSemaxanib;SU5416 
Molecular FormulaC15H14N2O 
Molecular Weight238.28 
SmileCc1cc([nH]c1/C=C\2/c3ccccc3NC2=O)C
InChiKeyWUWDLXZGHZSWQZ-WQLSENKSSA-N
InChiInChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8-
CAS Number204005-46-9
MDLMFCD09763655
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationyellow solid 
Purity98% 
Storage3 years -20ºCpowder 
Solubility5mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

51803 - Semaxanib (SU5416) | CAS 204005-46-9

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