Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 M, 20-fold more selective for VEGFR than PDGFR, lack of activity against EGFR, InsR and FGFR. Phase 3.
For research use only. We do not sell to patients.
| Name | Semaxanib (SU5416) | 
|---|---|
| Iupac Chemical Name | 2H-Indol-2-one,3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)- | 
| Synonyms | Semaxanib;SU5416 | 
| Molecular Formula | C15H14N2O | 
| Molecular Weight | 238.28 | 
| Smile | Cc1cc([nH]c1/C=C\2/c3ccccc3NC2=O)C | 
| InChiKey | WUWDLXZGHZSWQZ-WQLSENKSSA-N | 
| InChi | InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8- | 
| CAS Number | 204005-46-9 | 
| MDL | MFCD09763655 | 
| Related CAS | 
| Packaging | Price | Availability | Purity | Shipping Time | 
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry | 
| Formulation | yellow solid | 
|---|---|
| Purity | 98% | 
| Storage | 3 years -20ºCpowder | 
| Solubility | 5mg/ml in DMSO | 
| Handling | |
| Shipping Condition | Shipped under ambient temperature | 
| HS Code | 
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | 
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