Glycerol phenylbutyrate ( HPN-100 )
Catalog No: 230401
CAS Number: 611168-24-2
Purity: ≧98.0%
Glycerol phenylbutyrate, also known as HPN-100, is under trials in the treatment of certain inborn urea cycle disorders. The medication works by preventing the harmful buildup of ammonia in the body. Ammonia is a neurotoxic agent that is primarily generated in the intestine and detoxified in the liver. Toxic increases in systemic ammonia levels predominantly result from an inherited or acquired impairment in hepatic detoxification and lead to potentially life-threatening neuropsychiatric symptoms.
For research use only. We do not sell to patients.
Chemical Information
| Name | Glycerol phenylbutyrate ( HPN-100 ) |
|---|---|
| Iupac Chemical Name | propane-1,2,3-triyl tris(4-phenylbutanoate) |
| Synonyms | Glycerol phenylbutyrate ; HPN-100 ; Glyceryl tri-(4-phenylbutyrate) ; RAVICTI |
| Molecular Formula | C33H38O6 |
| Molecular Weight | 530.27 |
| Smile | O=C(OCC(OC(CCCC1=CC=CC=C1)=O)COC(CCCC2=CC=CC=C2)=O)CCCC3=CC=CC=C3 |
| InChiKey | ZSDBFLMJVAGKOU-UHFFFAOYSA-N |
| InChi | InChI=1S/C33H38O6/c34-31(22-10-19-27-13-4-1-5-14-27)37-25-30(39-33(36)24-12-21-29-17-8-3-9-18-29)26-38-32(35)23-11-20-28-15-6-2-7-16-28/h1-9,13-18,30H,10-12,19-26H2 |
| CAS Number | 611168-24-2 |
| Related CAS | 611168-24-2 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Colorless to Light yellow oil |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | DMSO : ≥ 150 mg/mL (282.67 mM) Ethanol : 50 mg/mL (94.22 mM; Need ultrasonic) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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