Zelasudil
Catalog No: 24014
CAS Number: 2365193-22-0
Purity: ≧98.0%
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-Associated Coiled-Coil Containing Protein Kinase 2 (ROCK2) which sits at a nodal point in cell signalling pathways, central to fibrosis.
For research use only. We do not sell to patients.
Chemical Information
| Name | Zelasudil |
|---|---|
| Iupac Chemical Name | 4-(5-((4-cyclopropyl-1H-indazol-5-yl)amino)-1-methyl-1H-1,2,4-triazol-3-yl)-N-(2,2-difluoroethyl)benzamide |
| Synonyms | Zelasudil ; RXC 007 ; RXC007 ; RXC-007 |
| Molecular Formula | C22H21F2N7O |
| Molecular Weight | 437.45 |
| Smile | O=C(NCC(F)F)C1=CC=C(C2=NN(C)C(NC3=C(C4CC4)C5=C(NN=C5)C=C3)=N2)C=C1 |
| InChiKey | HSZPZEGJQCFGDE-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H21F2N7O/c1-31-22(27-17-9-8-16-15(10-26-29-16)19(17)12-2-3-12)28-20(30-31)13-4-6-14(7-5-13)21(32)25-11-18(23)24/h4-10,12,18H,2-3,11H2,1H3,(H,25,32)(H,26,29)(H,27,28,30) |
| CAS Number | 2365193-22-0 |
| Related CAS | 2365193-22-0 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
