Zedoresertib (Debio 0123) is a brain-penetrant, highly selective WEE1 kinase inhibitor.
For research use only. We do not sell to patients.
| Name | Zedoresertib |
|---|---|
| Iupac Chemical Name | 3-(2,6-dichlorophenyl)-1-methyl-7-((3-methyl-4-(1-methylpiperidin-4-yl)phenyl)amino)-2,3-dihydropyrimido[4,5-d]pyrimidin-4(1H)-one |
| Synonyms | Debio-0123 ; Zedoresertib ; Debio 0123 ; Debio0123 |
| Molecular Formula | C26H28Cl2N6O |
| Molecular Weight | 510.17 |
| Smile | O=C1C2=CN=C(N=C2N(C)CN1C3=C(C=CC=C3Cl)Cl)NC4=CC=C(C(C)=C4)C5CCN(C)CC5 |
| InChiKey | VWHNEYAANMETIA-UHFFFAOYSA-N |
| InChi | InChI=1S/C26H28Cl2N6O/c1-16-13-18(7-8-19(16)17-9-11-32(2)12-10-17)30-26-29-14-20-24(31-26)33(3)15-34(25(20)35)23-21(27)5-4-6-22(23)28/h4-8,13-14,17H,9-12,15H2,1-3H3,(H,29,30,31) |
| CAS Number | 2243882-74-6 |
| Related CAS | 2243882-74-6 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |