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ZM 306416

Catalog No.: 122923
Cas No.: 690206-97-4
Purity : 98% 
122923 - ZM 306416 | CAS 690206-97-4

Catalog number : 122923

CAS number : 690206-97-4

Molecular Formula : C16H13ClFN3O2 

Molecular Weight : 333.745 

Iupac Chemical Name : N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine 

Smile : COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC

InChiKey : YHUIUSRCUKUUQA-UHFFFAOYSA-N

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SynonymsCB 676475; ZM-306416; ZM306416; CB-676475; CB676475 
Molecular FormulaC16H13ClFN3O2 
Molecular Weight333.745 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC
InChiKeyYHUIUSRCUKUUQA-UHFFFAOYSA-N
InChiInChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18/h3-8H,1-2H3,(H,19,20,21)
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ZM-306416 is a VEGFR inhibitor that inhibits Flk-1 (KDR) (IC50=100 nM) and Flt (IC50 =2 M); displays 4-fold selectivity over FGFR-1; inhibitor of c-Abl, Flt-1 and Src. 

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