ZL0454
Catalog No: 193281
CAS Number: 2229042-77-5
Purity: >98%
ZL0454 is a potent and selective BRD4 inhibitor. ZL0454 reduces airway inflammation and inhibits the TLR3-dependent innate immune gene program, including ISG54, ISG56, IL-8, and Groβ genes in cultured human small airway epithelial cells (hSAECs).
For research use only. We do not sell to patients.
Chemical Information
| Name | ZL0454 |
|---|---|
| Iupac Chemical Name | (E)-4-((2-Amino-4-hydroxy-5-methylphenyl)diazenyl)-N-cyclopentylbenzenesulfonamide |
| Synonyms | ZL-0454; ZL 0454; ZL0454 |
| Molecular Formula | C18H22N4O3S |
| Molecular Weight | 374.46 |
| Smile | O=S(C1=CC=C(/N=N/C2=CC(C)=C(O)C=C2N)C=C1)(NC3CCCC3)=O |
| InChiKey | IRKMSULWLDLTIK-QZQOTICOSA-N |
| InChi | InChI=1S/C18H22N4O3S/c1-12-10-17(16(19)11-18(12)23)21-20-13-6-8-15(9-7-13)26(24,25)22-14-4-2-3-5-14/h6-11,14,22-23H,2-5,19H2,1H3/b21-20+ |
| CAS Number | 2229042-77-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
