ZL0454是一种有效的选择性BRD4抑制剂。ZL0454减少气道炎症,抑制TLR3-依赖先天免疫基因程序,包括ISG54 ISG56,IL-8,Groβ基因在培养人类小气道上皮细胞(hSAECs)。
For research use only. We do not sell to patients.
| Name | ZL0454 |
|---|---|
| Iupac Chemical Name | (E)-4-((2-Amino-4-hydroxy-5-methylphenyl)diazenyl)-N-cyclopentylbenzenesulfonamide |
| Synonyms | ZL-0454; ZL 0454; ZL0454 |
| Molecular Formula | C18H22N4O3S |
| Molecular Weight | 374.46 |
| Smile | O=S(C1=CC=C(/N=N/C2=CC(C)=C(O)C=C2N)C=C1)(NC3CCCC3)=O |
| InChiKey | IRKMSULWLDLTIK-QZQOTICOSA-N |
| InChi | InChI=1S/C18H22N4O3S/c1-12-10-17(16(19)11-18(12)23)21-20-13-6-8-15(9-7-13)26(24,25)22-14-4-2-3-5-14/h6-11,14,22-23H,2-5,19H2,1H3/b21-20+ |
| CAS Number | 2229042-77-5 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色至白色固体 |
|---|---|
| Purity | >98% |
| Storage | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
| Solubility | 可溶于DMSO |
| Handling | |
| Shipping Condition | 可在常温下运输 |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |