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ZK-756326 dihydrochloride

Catalog No.: 16122850
Cas No.: 1780259-94-0
Purity : 98% 
16122850 - ZK-756326 dihydrochloride | CAS 1780259-94-0

Catalog number : 16122850

CAS number : 1780259-94-0

Molecular Formula : C21H30Cl2N2O3 

Molecular Weight : 429.382 

Iupac Chemical Name : ZK-756326 dihydrochloride 

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SynonymsZK-756326; ZK 756326; ZK756326; ZK-756326 dihydrochloride 
Molecular FormulaC21H30Cl2N2O3 
Molecular Weight429.382 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
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ZK-756326 is a potent, selective and non-peptide CCR8 chemokine receptor agonist. ZK 756326 inhibited the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 muM. ZK 756326 was a full agonist of CCR8, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1. 

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