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Y15 hydrochloride

Catalog No.: 17030112
Cas No.: 4506-66-5
Purity : 98% 
17030112 - Y15 hydrochloride | CAS 4506-66-5

Catalog number : 17030112

CAS number : 4506-66-5

Molecular Formula : C6H14Cl4N4 

Molecular Weight : 284.006 

Iupac Chemical Name : 1,2,4,5-benzenetetramine tetrahydrochloride 

Smile : Cl.Cl.Cl.Cl.C=1(C(=CC(=C(C1)N)N)N)N

InChiKey : BZDGCIJWPWHAOF-UHFFFAOYSA-N

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SynonymsY15 hydrochloride; Y15 tetrahydrochloride; Y 15; Y-15. FAK Inhibitor 14 
Molecular FormulaC6H14Cl4N4 
Molecular Weight284.006 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileCl.Cl.Cl.Cl.C=1(C(=CC(=C(C1)N)N)N)N
InChiKeyBZDGCIJWPWHAOF-UHFFFAOYSA-N
InChiInChI=1S/C6H10N4.4ClH/c7-3-1-4(8)6(10)2-5(3)9;;;;/h1-2H,7-10H2;4*1H
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Y15 hydrochloride, also known as FAK Inhibitor 14, is a direct FAK autophosphorylation inhibitor, blocking phosphorylation of Y397 with an IC50 value of about 1 M. Y15 decreases viability, clonogenicity, and cell attachment in thyroid cancer cell lines and synergizes with targeted therapeutics. Y15 was shown to decrease cancer growth in vitro and in vivo. 

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