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WP1066

Catalog No.: 122527
Cas No.: 857064-38-1
Purity : 98% 
122527 - WP1066 | CAS 857064-38-1

Catalog number : 122527

CAS number : 857064-38-1

Molecular Formula : C17H14BrN3O 

Molecular Weight : 356.217 

Iupac Chemical Name : (E)-3-(6-bromopyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide 

Smile : CC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N

InChiKey : VFUAJMPDXIRPKO-UHFFFAOYSA-N

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SynonymsWP 1066; WP-1066 
Molecular FormulaC17H14BrN3O 
Molecular Weight356.217 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N
InChiKeyVFUAJMPDXIRPKO-UHFFFAOYSA-N
InChiInChI=1S/C17H14BrN3O/c1-12(13-6-3-2-4-7-13)20-17(22)14(11-19)10-15-8-5-9-16(18)21-15/h2-10,12H,1H3,(H,20,22)
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WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 M and 2.43 M in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2, but not JAK1 and JAK3. 

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