WP1066
Catalog No: 122527
CAS Number: 857064-38-1
Purity: 98%
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 M and 2.43 M in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2, but not JAK1 and JAK3.
For research use only. We do not sell to patients.
Chemical Information
| Name | WP1066 |
|---|---|
| Iupac Chemical Name | (E)-3-(6-bromopyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide |
| Synonyms | WP 1066; WP-1066 |
| Molecular Formula | C17H14BrN3O |
| Molecular Weight | 356.217 |
| Smile | CC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N |
| InChiKey | VFUAJMPDXIRPKO-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H14BrN3O/c1-12(13-6-3-2-4-7-13)20-17(22)14(11-19)10-15-8-5-9-16(18)21-15/h2-10,12H,1H3,(H,20,22) |
| CAS Number | 857064-38-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
