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Voruciclib

Catalog No.: 178306
Cas No.: 1000023-04-0
Purity : 98.0%

Voruciclib, also known as P1446A-05, is a protein kinase inhibitor specific for the cyclin-dependent kinase 4 (CDK4) with potential antineoplastic activity.

For research use only. We do not sell to patients.

Chemical Information

NameVoruciclib
Iupac Chemical Name2-(2-Chloro-4-(trifluoromethyl)phenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-1-benzopyran-4-one
SynonymsP1446A05, P1446A-05, P1446A 05, Voruciclib.
Molecular FormulaC22H19ClF3NO5
Molecular Weight469.8412
SmileClC1=C(C=CC(=C1)C(F)(F)F)C=1OC2=C(C(C1)=O)C(=CC(=C2[C@H]2[C@@H](N(CC2)C)CO)O)O
InChiKeyMRPGRAKIAJJGMM-OCCSQVGLSA-N
InChiInChI=1S/C22H19ClF3NO5/c1-27-5-4-12(14(27)9-28)19-15(29)7-16(30)20-17(31)8-18(32-21(19)20)11-3-2-10(6-13(11)23)22(24,25)26/h2-3,6-8,12,14,28-30H,4-5,9H2,1H3/t12-,14+/m1/s1
CAS Number1000023-04-0
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Ordering Information

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Formulationoff-white solid
Purity98.0%
Storage-20 ℃ for 3 years
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

178306 - Voruciclib | CAS 1000023-04-0

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