Vepafestinib ( Synonyms: TAS0953 ; HM06)

Catalog No: 25166

CAS Number: 2129515-96-2

Purity: ≧98.0%

Vepafestinib, also known as HM06 and TAS0953, is a RET-selective inhibitor with enhanced CNS penetrance targets therapy-resistant mutants.

For research use only. We do not sell to patients.

Name	Vepafestinib ( Synonyms: TAS0953 ; HM06)
Iupac Chemical Name	4-amino-N-[4-(methoxymethyl)phenyl]-7-(1- methylcyclopropyl)-6-[3-(morpholin-4-yl)prop-1-yn-1- yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide
Synonyms	Vepafestinib ; HM06 ; TAS0953 ; HM-06 ; TAS-0953 ; HM 06 ; TAS 0953 ; vepafestinibum
Molecular Formula	C26H30N6O3
Molecular Weight	474.57
Smile	O=C(C1=C(C#CCN2CCOCC2)N(C3(C)CC3)C4=NC=NC(N)=C41)NC5=CC=C(COC)C=C5
InChiKey	SFXVRNLGOSAWIV-UHFFFAOYSA-N
InChi	InChI=1S/C26H30N6O3/c1-26(9-10-26)32-20(4-3-11-31-12-14-35-15-13-31)21(22-23(27)28-17-29-24(22)32)25(33)30-19-7-5-18(6-8-19)16-34-2/h5-8,17H,9-16H2,1-2H3,(H,30,33)(H2,27,28,29)
CAS Number	2129515-96-2
Related CAS	2129515-96-2

Packaging	Price	Availability	Purity	Shipping Time
Bulk		Enquiry	Enquiry	Enquiry

Formulation	Light yellow to yellow (Solid)
Purity	≧98.0%
Storage	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
Solubility	Soluble in DMSO (DMSO : ≥ 100 mg/mL)
Handling	Refer to MSDS
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code	2934200090

Coming soon.

Targets	RET inhibitor
Mechanism	Vepafestinib, also known as HM06 and TAS0953, is a RET-selective inhibitor with enhanced CNS penetrance targets therapy-resistant mutants.
Cell study
Animal study
Clinical study

Not available