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Venglustat ( ibiglustat )

Catalog No: 822223
CAS Number: 1401090-53-6
Purity: ≧98.0%

Ibiglustat (Venglustat) 是一种具有口服活性的,可透过血脑屏障的葡萄糖神经酰胺合成酶 (GCS) 抑制剂。Ibiglustat 可用于研究戈谢病 3 型、与 GBA 突变相关的帕金森病、法布瑞氏症、GM2 神经节苷脂病和常染色体显性多囊肾病。

For research use only. We do not sell to patients.

Chemical Information

NameVenglustat ( ibiglustat )
Iupac Chemical Name(3S)-1-azabicyclo[2.2.2]octan-3-yl N-{2-[2-(4-fluorophenyl)- 1,3-thiazol-4-yl]propan-2-yl}carbamate
SynonymsGZ-402671 ; GZ402671 ; GZ 402671 ; SAR402671 ; SAR-402671 ; SAR 402671 ; Genz-682452-AA ; Ibiglustat ; GZ-452 ; Genz-682452 ; Venglustat ;
Molecular FormulaC20H24FN3O2S
Molecular Weight389.49
SmileO=C(O[C@@H]1CN2CCC1CC2)NC(C)(C3=CSC(C4=CC=C(F)C=C4)=N3)C
InChiKeyYFHRCLAKZBDRHN-MRXNPFEDSA-N
InChiInChI=1S/C20H24FN3O2S/c1-20(2,17-12-27-18(22-17)14-3-5-15(21)6-4-14)23-19(25)26-16-11-24-9-7-13(16)8-10-24/h3-6,12-13,16H,7-11H2,1-2H3,(H,23,25)/t16-/m1/s1
CAS Number1401090-53-6
Related CAS1401090-53-6 ( free base ) ; 1629063-79-1 (HCl) ; 1629063-80-4 (succinic acid) ; 1629063-78-0 (malate)

Ordering Information

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Formulation类白色固体
Purity≧98.0%
Storage0-4℃,可保存几天到几周;-20℃,可保存 几个月。
Solubility溶于DMSO等有机溶剂
HandlingRefer to MSDS
Shipping Condition可以在室温下进行运输。
HS Code2934200090
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

822223 - Venglustat ( ibiglustat )  | CAS 1401090-53-6

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