Velzatinib is an orally bioavailable small molecule inhibitor of multiple mutated forms of mast/stem cell factor receptor KIT (c-Kit; SCFR), with potential antineoplastic activity.
For research use only. We do not sell to patients.
| Name | Velzatinib (IDRX-42, M-4205) |
|---|---|
| Iupac Chemical Name | N-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine |
| Synonyms | Velzatinib ; IDRX-42 ; M-4205 ; IDRX42 ; M4205 ; IDRX 42 ; M 4205 ; |
| Molecular Formula | C29H32N8O |
| Molecular Weight | 508.27 |
| Smile | CN1N=CC(C2=CC=C(CNC3=NC=NC(C4=CN=C5C=C(OCCCN6CCCC6)C=CN54)=C3)C=C2)=C1 |
| InChiKey | LVMAULGVWBINFP-UHFFFAOYSA-N |
| InChi | InChI=1S/C29H32N8O/c1-35-20-24(18-34-35)23-7-5-22(6-8-23)17-30-28-16-26(32-21-33-28)27-19-31-29-15-25(9-13-37(27)29)38-14-4-12-36-10-2-3-11-36/h5-9,13,15-16,18-21H,2-4,10-12,14,17H2,1H3,(H,30,32,33) |
| CAS Number | 2590556-80-0 |
| Related CAS | 2590556-80-0 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |