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VU0467154

Catalog No.: 18576
Cas No.: 1451993-15-9
Purity : ≧98.0%

VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor (mAChR), potentiating the response to ACh with pEC50s of 7.75, 6.2 and 6 for rat, human and cynomolgus monkey M4 receptor, respectively.

For research use only. We do not sell to patients.

Chemical Information

NameVU0467154
Iupac Chemical Name5-Amino-3,4-dimethyl-N-[[4-[(trifluoromethyl)sulfonyl]phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide
SynonymsVU0467154 ; VU-0467154 ; VU 0467154
Molecular FormulaC17H15F3N4O3S2
Molecular Weight444.4472
SmileO=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NCC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3
InChiKeyUDSFKIFLJPECRN-UHFFFAOYSA-N
InChiInChI=1S/C17H15F3N4O3S2/c1-8-9(2)23-24-16-12(8)13(21)14(28-16)15(25)22-7-10-3-5-11(6-4-10)29(26,27)17(18,19)20/h3-6H,7,21H2,1-2H3,(H,22,25)
CAS Number1451993-15-9
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationyellow solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

18576 - VU0467154 | CAS 1451993-15-9

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