Uprosertib (GSK2141795)
Catalog No: 16070901
CAS Number: 1047634-65-0
Purity: 98% by HPLC
Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively
For research use only. We do not sell to patients.
Chemical Information
| Name | Uprosertib (GSK2141795) |
|---|---|
| Iupac Chemical Name | 2-Furancarboxamide, N-[(1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)- |
| Synonyms | GSK795 |
| Molecular Formula | C18H16Cl2F2N4O2 |
| Molecular Weight | 429.25 |
| Smile | NC[C@H](CC1=CC(=C(C=C1)F)F)NC(=O)C=1OC(=C(C1)C1=C(C=NN1C)Cl)Cl |
| InChiKey | AXTAPYRUEKNRBA-JTQLQIEISA-N |
| InChi | InChI=1S/C18H16Cl2F2N4O2/c1-26-16(12(19)8-24-26)11-6-15(28-17(11)20)18(27)25-10(7-23)4-9-2-3-13(21)14(22)5-9/h2-3,5-6,8,10H,4,7,23H2,1H3,(H,25,27)/t10-/m0/s1 |
| CAS Number | 1047634-65-0 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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