Upacicalcet
Catalog No: 192142
CAS Number: 1333218-50-0
Purity: ≧98.0%
Upacicalcet (formerly SK-1403/AJT240) is a novel non-peptide calcimimetic agent that acts as a calcium-sensing receptor (CaSR) agonist for the treatment of secondary hyperparathyroidism (SHPT) in chronic kidney disease (CKD).
For research use only. We do not sell to patients.
Chemical Information
| Name | Upacicalcet |
|---|---|
| Iupac Chemical Name | (2S)-2-amino-3-{[(3-chloro-2-methyl-5-sulfophenyl)carbamoyl]amino}propanoic acid |
| Synonyms | Upacicalcet ; SK-1403 ; AJT240 ; SK1403 ; AJT-240 ; SK 1403 ; AJT 240 |
| Molecular Formula | C11H14ClN3O6S |
| Molecular Weight | 351.75 |
| Smile | O=C(O)[C@@H](N)CNC(NC1=CC(S(=O)(O)=O)=CC(Cl)=C1C)=O |
| InChiKey | LHEYGVSDVBEYQF-QMMMGPOBSA-N |
| InChi | InChI=1S/C11H14ClN3O6S/c1-5-7(12)2-6(22(19,20)21)3-9(5)15-11(18)14-4-8(13)10(16)17/h2-3,8H,4,13H2,1H3,(H,16,17)(H2,14,15,18)(H,19,20,21)/t8-/m0/s1 |
| CAS Number | 1333218-50-0 |
| Related CAS | 1333218-50-0 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature |
| HS Code | 2934200090 |
Coming soon.
| Targets | CaSR inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
